Instytut Biologii Medycznej PAN

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Publikacje


2020

  1. Pathak S, Wilczyński JR, Paradowska E. Factors in oncogenesis: viral infections in ovarian cancer. Cancers, 2020, 12(3): 561. doi: 10.3390/cancers12030561
  2. Jabłońska A, Neumayer C, Bolliger M, Burghuber C, Klinger M, Demyanets S, Nanobachvili J, Huk I. Insight into the expression of toll-like receptors 2 and 4 in patients with abdominal aortic aneurysm.  Mol Biol Rep, 2020, March 7. doi: 10.1007/s11033-020-05366-x

2019

  1. Paradowska E, Jabłońska A, Studzińska M, Wilczyński M, Wilczyński JR. Detection and genotyping of CMV and HPV in tumors and fallopian tubes from epithelial ovarian cancer patients. Sci Rep, 2019, 9(1): 19935. doi: 10.1038/s41598-019-56448-1
  2. Paradowska E, Jabłońska A, Studzińska M, Kasztelewicz B, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Woźniakowska-Gęsicka T, Czech-Kowalska J. Distribution of the CMV glycoprotein gH/gL/gO and gH/gL/pUL128/pUL130/pUL131A complex variants and associated clinical manifestations in infants infected congenitally or postnatally. Sci Rep, 2019, 9(1): 16352. doi: 10.1038/s41598-019-52906-y
  3. Mieczkowski A, Kierozalska A, Białek-Pietras M, Goszczyński TM, Janczak S, Olejniczak AB, Studzińska M, Paradowska E, Leśnikowski ZJ. Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties. Fut Med Chem, 2019, 11(11): 1267-1284. doi: 10.4155/fmc-2018-0517
  4. Saftić D, Studzińska M, Paradowska E, Piantanida I, Baranović G, Białek-Pietras M, Leśnikowski ZJ. Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugates. Bioorg Chem, 2020, 94:103466. doi: 10.1016/j.bioorg.2019.103466

2018

  1. Jabłońska A, Neumayer C, Bolliger M, Gollackner B, Klinger M, Paradowska E, Nanobachvili J, Huk I. Analysis of host Toll-like receptor 3 and RIG-I-like receptor gene expression in patients with abdominal aortic aneurysm. J Vasc Surg, 2018, 68(6S): 39S-46S. doi: 10.1016/j.jvs.2017.10.087
  2. Jabłońska A, Studzińska M, Suski P, Kalinka J, Paradowska E. Enhanced expression of IFI16 and RIG-I in human third-trimester placentas following HSV-1 infection. Clin Exp Immunol, 2018, 193(2): 255-63. doi: 10.1111/cei.13143
  3. Saftić D, Žinić B, Glavaš-Obrovac L, Studzińska M, Paradowska E, Leśnikowski ZJ. Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives. Nucleosides, Nucleotides Nucleic Acids, 2018, 37(7): 397-414. doi:  10.1080/15257770.2018.1485932
  4. Białek-Pietras M, Olejniczak AB, Paradowska E, Studzińska M, Jabłońska A, Leśnikowski ZJ. Synthesis, susceptibility to enzymatic phosphorylation, cytotoxicity and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates. J Organomet Chem, 2018, 865: 166-72. doi: 10.1016/j.jorganchem.2018.03.026

2017

  1. Kowalski  ML, Wardzynska  A, Studzinska  M, Pawelczyk  M, Lesnikowski  ZJ, Paradowska E. Cytomegalovirus DNA is highly prevalent in the blood of patients with asthma and is associated with age and asthma traits. Allergy, 2017, 72(12): 2035-8. doi: 10.1111/all.13233
  2. Kosenko I, Ananyev I, Druzina A, Godovikov I, Laskova J, Bregadze V, Studzinska M, Paradowska E, Leśnikowski ZJ, Semioshkin A. Disubstituted cobalt bis(1,2-dicarbollide)(-I) terminal alkynes: Synthesis, reactivity in the Sonogashira reaction and application in the synthesis of cobalt bis(1,2-dicarbollide)(-I) nucleoside conjugates. J Organomet Chem, 2017, 849-50: 142-149. doi: 10.1016/j.jorganchem.2017.02.030
  3. Studzińska M, Jabłońska A, Wiśniewska-Ligier M, Nowakowska D, Gaj Z, Leśnikowski ZJ, Woźniakowska-Gęsicka T, Wilczyński J, Paradowska E. Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children. PLoS One, 2017,12(1):e0169420. doi: 10.1371/journal.pone.0169420
  4. Wujcicka W, Paradowska E, Studzińska M, Wilczyński J, Nowakowska D. TLR2 2258 G>A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus. Virol J, 2017, 14(1): 1-12. doi: 10.1186/s12985-016-0679-z
  5. Wujcicka W, Paradowska E, Studzińska M, Wilczyński J, Nowakowska D. Toll-like receptors genes polymorphisms and the occurrence of HCMV infection among pregnant women. Virol J, 2017, 14(1): 64. doi: 10.1186/s12985-017-0730-8
  6. Wujcicka W, Wilczyński J, Paradowska E, Studzińska M, Nowakowska D. The role of single nucleotide polymorphisms, contained in proinflammatory cytokine genes, in the development of congenital infection with human cytomegalovirus in fetuses and neonates. Microb Pathog, 2017,105: 106-16. doi: 10.1016/j.micpath.2017.02.017

2016

  1. Laskova J, Kozlova A,  Białek-Pietras M, Studzińska M, Paradowska E, Bregadze V, Leśnikowski ZJ, Semioshkin A. Reactions of closo-dodecaborate amines. Towards novel bis-(closododecaborates) and closo-dodecaborate conjugates with lipids and non-natural Nucleosides. J Organomet Chem, 2016, 807: 29-35. doi:10.1016/j.jorganchem.2016.02.009
  2. Paradowska E, Jabłońska A, Studzińska M, Skowrońska K, Suski P,  Wiśniewska-Ligier M, Woźniakowska-Gęsicka T, Nowakowska D, Gaj Z, Wilczyński J,  Leśnikowski ZJ. TLR9 -1486T/C and 2848C/T SNPs are associated with human cytomegalovirus infection in infants. PLoS One, 2016, 11(4): e0154100. doi: 10.1371/journal.pone.0154100
  3. Adamska A, Rumijowska-Galewicz A, Ruszczynska A,  Studzińska M, Jabłońska A, Paradowska E, Bulska E, Munier-Lehmann H, Dziadek J, Leśnikowski ZJ, Olejniczak AB. Anti-mycobacterial activity of thymine derivatives bearing boron clusters. Eur J Med Chem, 2016, 121: 71-81. doi: 10.1016/j.ejmech.2016.05.030

2015

  1. Paradowska E, Studzińska M, Suski P, Kasztelewicz B, Wiśniewska-Ligier M, Zawilińska B, Gaj Z, Nowakowska D. Human cytomegalovirus UL55, UL144, and US28 genotype distribution in infants infected congenitally or postnatally. J Med Virol, 2015, 87(10): 1737-48. doi: 10.1002/jmv.24222
  2. Rycel M, Wujcicka W, Zawilińska B, Paradowska E, Suski P, Gaj Z, Wilczyński J, Leśnikowski ZJ,  Nowakowska D. Mixed infections with distinct cytomegalovirus glycoprotein B genotypes in Polish pregnant women, foetuses, and newborns. Eur J Clin Microbiol Infect Dis, 2015, 34(3): 585-91. doi: 10.1007/s10096-014-2266-9
  3. Lewandowska-Polak A, Brauncajs M, Paradowska E, Jarzębska M, Kurowski M, Moskwa S,  Leśnikowski ZJ, Kowalski ML. Human parainfluenza virus type 3 (HPIV3) induces production of IFN-gamma and RANTES in human nasal epithelial cells (HNECs). J Inflamm (Lond), 2015, 12: 16. doi: 10.1186/s12950-015-0054-7
  4. Wujcicka W, Paradowska E, Studzińska M, Gaj Z, Wilczyński J, Leśnikowski Z, Nowakowska D.  TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus. PLoS One, 2015, 10(4): e0122831. doi:10.1371/journal.pone.0122831
  5. Białek-Pietras M, Olejniczak AB, Paradowska E, Studzińska M, Suski P, Jabłońska A,  Leśnikowski  ZJ. Synthesis and in vitro antiviral activity of lipophilic pyrimidine nucleoside/carborane conjugates. J Organomet Chem, 2015, 798: 99-105. doi:10.1016/j.jorganchem.2015.07.002

2014

  1. Paradowska E, Jabłońska A, Płóciennikowska A, Studzińska M, Suski P, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Kasztelewicz B, Woźniakowska-Gęsicka T, Leśnikowski ZJ. 
    Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections. Virology, 2014, 462-463C:207-17. doi: 10.1016/j.virol.2014.06.020
  2. Paradowska E, Jabłońska A, Studzińska M, Kasztelewicz B, Zawilińska B, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Woźniakowska-Gęsicka T, Kosz-Vnenchak M, Leśnikowski ZJ. 
    Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children. J Med Virol, 2014, 86(8), 1421-7. doi: 10.1002/jmv.23906 
  3. Jabłońska A, Paradowska E, Studzińska M, Suski P, Nowakowska D, Wiśniewska-Ligier M, Woźniakowska-Gęsicka T, Wilczyński J, Leśnikowski ZJ. Relationship between Toll-like receptor 2 Arg677Trp and Arg753Gln and Toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection. Int J Infect Dis, 2014,25: 11-5. doi: 10.1016/j.ijid.2014.04.001
  4. Gaj Z, Wilczyński J, Nowakowska-Głąb A, Boakye-Agyeman F, Paradowska E, Leśnikowski ZJ, Nowakowska D. Decrease in 3-nitrotyrosine in the amniotic fluid of women with cytomegalovirus infection. J Obstet Gynaecol2014,34(3): 251-4. doi: 10.3109/01443615.2013.851656
  5. Ilinova A, Semioshkin A, Lobanova I, Bregadze VI, Mironov AF, Paradowska E, Studzińska M, Jabłońska A, Białek-Pietras M, Leśnikowski ZJ. Synthesis, cytotoxicity and antiviral activity studies of the conjugates of cobalt bis(1,2-dicarbollide)(-I) with 5-ethynyl-2'-deoxyuridine and its cyclic derivatives. Tetrahedron, 2014, 70: 5704-10. doi: 10.1016/j.tet.2014.06.072
  6. Jabłońska A, Paradowska E. Rola receptorów RIG-I-podobnych w odpowiedzi przeciwwirusowej. Postępy Hig Med Dosw, 2014, 68: 541-56.

2013

  1. Paradowska E, Jabłońska A, Studzińska M, Suski P, Kasztelewicz B, Zawilińska B, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Woźniakowska-Gęsicka T, Czech-Kowalska J, Lipka B, Kornacka M, Pawlik D, Tomasik T, Kosz-Vnenchak M, Leśnikowski ZJ. Cytomegalovirus gN and gH genotypes distribution and clinical sequels in infantsJ Clin Virol, 2013, 58(1):271-5. doi: 10.1016/j.jcv.2013.05.024
  2. Olejniczak AB, Adamska AM, Paradowska E, Studzińska M, Suski P, Leśnikowski ZJ. 
    Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator. Acta Pol Pharm,2013, 70(3): 489-504.
  3. Semioshkin A, Ilinova A, Lobanova I, Bregadze V, Paradowska E, Studzińska M, Jabłońska A, Lesnikowski ZJ. Synthesis of the first conjugates of 5-ethynyl-2'-deoxyuridine with closo-dodecaborate and cobalt-bis-dicarbollide boron clusters. Tetrahedron, 2013, 69(37): 8034-41. doi: 10.1016/j.tet.2013.06.100
  4. Rycel M, Gaj Z, Wilczyński J, Paradowska E, Studzińska M, Suski P, Nowakowska D. Ocena związku poziomu wiremii HCMV u matki z przebiegiem ciąży i stanem urodzeniowym noworodków. Ginekol Pol,2013, 84(12): 1005-11.